Biocomputing Group

Prof B. Jayaram  
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(i). Co-Chair, Data Management Committee, DBT (2024-2027).

(ii). Mentor, Supercomputing Facility for Bioinformatics & Computational Biology, IIT Delhi.

(iii). Emeritus Professor, Department of Chemistry, IITD (since July, 2019-Sept., 2023)

(iv). Professor, Department of Chemistry & Professor, Kusuma School of Biological Sciences, IIT Delhi.

(v). Coordinator, Supercomputing Facility for Bioinformatics & Computational Biology, IIT Delhi.

(vi). Ph.D. (1982-1986), City Univ. of New York, USA.

(vii). Post Doctoral Fellow (1987-88), Columbia University, USA.

(viii). Senior Research Associate (1989-90), Wesleyan University, USA.

(ix). Recipient of Chemical Research Society of India Medal (2000)

(x). Member of the National Task Force on Bioinformatics of Department of Biotechnology (DBT) (till 2009 & 2014 onwards)

(xi). Member of Physical Chemistry Programme Advisory Committee of the Department of Science & Technology (DST) (2004 -2007)

(xii). Member of Organic Chemistry Programme Advisory Committee of the DST (2007-2011).

(xiii). Member of the Working Group on Bioinformatics of Department of Information Technology (2007-2011)

(xiv). Vice President of Indian Biophysical Society (2006-2008).

(xv). Head, Department of Chemistry, IIT Delhi (Sept. 2006- Aug. 2009).

(xvi). Founder Coordinator, Kusuma School of Biological Sciences, IIT Delhi (2008- 2014).

(xvii). Member of FIST Committee of DST for Chemical Sciences (2009-2011)

(xviii). Member of National Committee of IUPAB (2008-2011).

(xix). Member of the Bioinformatics Task Force of Indian Council of Medical Research (2012-2013)

(xx). Member of the Editorial Board of Journal of Molecular Graphics & Modeling (2009-2011).

(xxi). Chairman, DBT's committee on promotion and popularization of Biotechnology (2009-2013).

(xxii) Member of Biophysics, Biochemistry & Molecular Biology Programme Advisory Committee of the DST (2012-2014).

(xxiii). Guided several PhDs (27 completed, 2 in progress); published over 150 papers and presented over 300 invited talks in national/international journals & conferences.

(xxiv). Responsible (a) for developing Chemgenome, Bhageerath & Sanjeevini methods & softwares for genome annotation, protein tertiary structure prediction & computer aided drug design respectively, (b) for setting up a multi-teraflop supercomputing facility for Bioinformatics & Computational Biology at IIT Delhi, and (c) for making the hardware and software freely accessible at (www.scfbio-iitd.res.in) to the global scientific user community.

(xxv). Faculty facilitator/Founder Director for two start-up companies (Leadinvent incubated at IIT, Delhi from 2006-2009 & Novoinformatics, under incubation at IIT Delhi from 2011-2014).

(xxvi). Recipient of IBM Faculty Award (2014-2015).

(xxvii). Recognized as one of the top five bioinformaticians in the country https://bioinformaticsreview.com/awards2018

Research Interest 
Biomolecular modeling and simulation in relation to Genome Analysis, Protein Structure Prediction and Drug Design.

During his Dhanvantari (Genome→Gene→Protein→Drug pathway) scientific journey, Prof. Jayaram with his students and colleagues made several important discoveries of relevance to bimolecular function. One was the conjugate rule among nucleic acid bases which explained degeneracies in genetic code and paved the way for a physico-chemical approach to genome annotation. This was followed by their discovery that energetic and structural properties of DNA sequences conveyed their functional destiny as demonstrated by them for gene, promoter, intron-exon boundary detections. Most notably, sequence to structure and dynamics to function was an established axiom in protein science. Their studies demonstrated that this axiom was true for nucleic acids as well. On the protein front, they discovered that just four physico-chemical properties of amino acids not only explained the existence of the magic number 20 for naturally occurring amino acids, but also set very high water mark for homology modelling and function prediction. They also found that millions of proteins chronicled till date shared a similar stoichiometry with very small standard deviations in their amino acid compositions which they called as the margin of life. Equally interesting was the observation that there was a universality in the spatial distribution of the C-alpha atoms. They also demonstrated that higher order Ramachandran maps carried sufficient information to build tertiary structures. Their analyses of the configurational space of proteins suggested, when higher order spatial correlations of amino acid residue neighbours were included, that protein folding was a convergent problem as opposed to the then conventional wisdom. Alphafold has now proved it. The Sanjeevini software they built for computer aided drug discovery, is comprised of several new methods for active site detection, docking and rapid screening of large libraries of small molecules etc.. Sanjeevini software suite has already delivered experimentally validated molecules against HAV, HBV, CHIKV and fungal infections, breast cancer and malaria.

Email Id : bjayaram[at]scfbio-iitd.res.in  bjayaram[at]chemistry.iitd.ac.in

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Prof B. Jayaram
Prof. Ashok Kumar Patel  

PI, Supercomputing Facility for Bioinformatics & Computational Biology, IIT Delhi.

Web page

Email Id : ashokpatel@bioschool.iitd.ac.in

Ashok Patel
Prof. Ashok Kumar Patel
Dr. Shashank Shekhar  

Principal Research Scientist

Area of work: High Performance Computing , Cluster & Resource Management.

Area of interest: MPI implementation on Linux and Solaris based High end Servers, Grid technology, Shell Scripting.

Email Id : shashank[at]scfbio-iitd.res.in

Dr. Shashank Shekhar
Dr. Shashank Shekhar
Ms. Vandana  

Research Scientist

Area of work:  Website designing and database management

Email Id : vandana[at]scfbio-iitd.res.in

Vandana
Ms. Vandana
Ms. Puneeta  

Sr. Project Assistant (Admin.)

Email Id : puneeta[at]scfbio-iitd.res.in

Puneeta
Ms. Puneeta
Mr. A. Mohan Rao  

Sr. Project Assistant (Admin.)

Email Id : amohanrao[at]scfbio-iitd.res.in

A. Mohan Rao
Mr. A. Mohan Rao
Mr. Dinesh Sharma  

PhD Student
Area of work: Computational genomics and experimental validation.

Email Id : dinesh[at]scfbio-iitd.res.in

Dinesh
Mr. Dinesh Sharma
Mr. Dheeraj Chaurasia  

Project Scientist
Area of work: Computer Aided Drug Discovery, Web Development, Database Development.
Area of Interest: MD Simulations and Web Development.

Email Id : dheeraj[at]scfbio-iitd.res.in

Dheeraj
Mr. Dheeraj Chaurashia
Mr. Arinjoy Datta  

PhD Student
Area of work: Investigations of physico-chemical interactions of enzymes leading to the origin of life. 
Area of Interest: Computational Biology, Proteomics, Molecular Evolution, Origin of Life.

Email Id : arinjoy[at]scfbio-iitd.res.in

Arinjoy
Mr. Arinjoy
Ms. Danish Aslam 

Project Scientist
Area of work: Computational Genomics and Machine Learning/Deep Learning in Bioinformatics
Area of Interest: Computational Genomics and Machine Learning Techniques in Bioinformatics

Email Id : daslam0786@gmail.com

Danish Aslam
Ms. Danish Aslam
Mr. Aman Sharma  

Project Scientist
Area of work: Molecular Dynamics Simulations based Drug Design. 
Area of Interest: Computational biology and Drug Discovery.

Email Id :  contactamansharma00@gmail.com

Aman Sharma
Mr. Aman Sharma
Ms. Munesh 

Sr. Project Assistant (Admin)

Email Id : cmunesh610@gmail.com

Munesh
Ms. Munesh
Dr. Tarun Jain  

Scientist, Ranbaxy

NDDR, Plot No.20, Sector-18, RZD-II,Gurgaon-122001

Email Id : Tarun.Jain[at]ranbaxy.com

 
Dr. Saher Afshan Shaikh  

Postdoctoral Researcher, Theoretical and Computational Biophysics

3015 Beckman Institute, 405 N Mathews Ave, Urbana, IL 61801, USA

Email Id : shaikh[at]illinois.edu

 
Dr. E. Rajasekaran  

Associate Professor, Department of Bioinformatics

School of Biotechnology and Health Science,Karunya University Coimbatore - 641114 Tamil Nadu.

Email Id : ersekaran[at]gmail.com

Rajasekaran
Dr. Nidhi Arora  

Scientist, Roche 3431

Hillview, Palo Alto LLC, CA

Email Id : nidhiarora[at]roche.com

Dr. Surjit Dixit  

Chief Technology Officer, Zymeworks Inc

540-1385 West 8th Avenue,Vancouver, BC, Canada, V6H 3V9

Email Id : sdixit[at]zymeworks.com

Dr. Parul Kalra  

Email Id : parbhatia[at]rediffmail.com

Dr. Suhas Vasant Vasaikar  

Dr. N. Latha  

Reader & Head, Department of Biochemistry

Coordinator, Bioinformatics Facility

Sri Venkateswa College, Dhaula Kuan, New Delhi-110021

Email Id : lata_svc[at]rediffmail.com[at]

Dr. Pooja Narang  

Research Associate, Department of Biochemistry & Molecular Biophysics

University of Arizona, Tucson AZ

Email Id : pooja.narang[at]rediffmail.com[at]

Dr. Kumkum Bhushan  

Technical Expert-Intellectual Property 

United Lex

Email Id : kumkum[at]scfbio-iitd.res.in

Kumkum Bhushan
Dr. Poonam Singhal  

Assistant Professor

Hansraj College, University of Delhi

Email Id : poonam[at]scfbio-iitd.res.in

Poonam Singhal
Dr. Garima Khandelwal  

 

Email Id : garima[at]scfbio-iitd.res.in

Garima Khandelwal  
Mr. Ali Khosravi  


Email Id : ali[at]scfbio-iitd.res.in

Ali
Dr. Tanya Singh  


Email Id : tanya[at]scfbio-iitd.res.in

Tanya Singh
Dr. Goutam Mukherjee  


Email Id : goutam[at]scfbio-iitd.res.in

 
Dr. Priyanka Dhingra  


Email Id : priyanka[at]scfbio-iitd.res.in

Priyanka Dhingra
Dr. Avinash Mishra  


Email Id : avinash[at]scfbio-iitd.res.in

Avinash Mishra
Mr. Samarprit Chakraborty  

Email Id : samarprit[at]scfbio-iitd.res.in

Samarprit
Dr. Ashutosh Shandilya  


Email Id : ashutosh[at]scfbio-iitd.res.in

Ashutosh
Dr. Anjali Soni  

Email Id : anjali[at]scfbio-iitd.res.in

Anjali
Dr. Rahul Kaushik  

Email Id : rahul[at]scfbio-iitd.res.in

Rahul
Dr. Debarati Dasgupta  


Email Id : debarati[at]scfbio-iitd.res.in

Debarati
Dr. Pradeep Pant  

PhD. Student

Area of work: Genome Analysis.

Email Id : pradeep[at]scfbio-iitd.res.in

Pradeep
Mr. Akhilesh Mishra  

PhD. Student

Area of work: Genome Analysis.

Email Id : akhilesh[at]scfbio-iitd.res.in

Akhilesh
Dr. Abhilash Jayaraj  

Project Scientist

Area of work: Software development and application for scaffold and ligand based drug design. Molecular dynamics studies of proteins and protein-ligand complexes.

Research interest: In silico drug designing.

Email Id : abhilash[at]scfbio-iitd.res.in

Abhilash
Dr. Ankita Singh  

Research Scientist

Area of work:  Protein Structure Prediction & Develpoment of P.vivax database.

Email Id : ankita[at]scfbio-iitd.res.in

ankita
Dr. Ankita
Ms. Ruchika Bhat  

PhD. Student

Area of work: Genome Analysis.

Email Id : ruchika[at]scfbio-iitd.res.in

Ms. Ruchika Bhat
Ms. Ruchika Bhat
Ms. Amita  

PhD. Student

Area of work: In Silico Protein Folding.

Email Id : amita[at]scfbio-iitd.res.in

amita
Ms. Amita
Dr. Shashank Shekhar  

Principal Research Scientist

Email Id : shashank[at]scfbio-iitd.res.in

Dr. Shashank Shekhar
Dr. Shashank Shekhar

Mr. Surojit Bose  

COO & Co-founder

Leadinvent , IIT Delhi-110016

Email Id : surojit[at]leadinvent.com

surojit
Mr. Pankaj Sharma  

CEO & Co-founder

Leadinvent, IIT Delhi-110016

Email Id : pankaj[at]leadinvent.com

pankaj
Mr. Praveen Agrawal  

CTO & Co-founder

Leadinvent, IIT Delhi-110016

Email Id : praveen[at]leadinvent.com

praveen
Mr. Vidhu S. Pandey  

Lead Engineer

Engineering and R & D Services 

HCL Technologies, Sec 60, NOIDA

Email Id : pandey_vidhu[at]yahoo.com

Mr. Anuj Gupta  

Infosys, Chandigarh

Email Id : anujgupta79@gmail.com

Anuj
Ms. Gurvisha Sandhu

Research Scientist, Lead Invent


Dr. Shailesh Tripathi  

U.K.,

Email Id : shailesh.tripathy@gmail.com

Shailesh Tripathi
Dr. Anju Khanna

IPR Consultant, New Delhi

Email Id : Anjub66[at]hotmail.com

Dr. Piyush Kumar Shukla

Managing Director

Dedicated Academy Pvt Ltd., New Delhi-110067

Email Id : piyushks[at]gmail.com

piyush
Dr. Achintya Das

Strand Life Sciences

237, Sir CV Raman Avenue, Bangalore-560080

Dr. Sandhya Shenoy  

Ph.D.

Research Interest
Protein Structure Prediction. Structure determination of drug targets using computational protocols.

Email Id : srshenoyiitd@gmail.com

Sandhya Shenoy
Mr. Dhrubajyoti Biswas  


Email Id : dhruva[at]scfbio-iitd.res.in

Dhruba
Ms. Pallavi  

Email Id : pallavi[at]scfbio-iitd.res.in

pallavi
Mr. Sahil Kapoor  

CEO & Co-founder

Novo Informatics, IIT Delhi

Email Id : sahil.kpr84@gmail.com

sahil
Ms. Rebecca Lee  

Project Trainee

Wesleyan University, USA

becky
Dr. Bharat Lakhani  


Email Id : lakhbharat@gmail.com

bharat
Mr. Satyanarayan Rao  


 

Email Id : satyanarayan.iiitm@gmail.com

satya
Mr. Navneet Singh Tomar  


 

Email Id : navneet.tomar87@gmail.com

Navneet
Ms. Preeti Bisht

Email Id : priti_762004@yahoo.co.in

Preeti Bisht
Ms. Varsha Singh  

Email Id : varsha[at]scfbio-iitd.res.in

varsha
Mr. R. Nagarajan  


Email Id : nagarajan[at]scfbio-iitd.res.in

R. Nagarajan
Mr. Ali Khosravi  


Email Id : mralikhosravi[at]gmail.com

Ali
Mr. Manpreet Singh  

Senior Lab Assistant 

IIT Delhi

Email Id : java.manpreet@gmail.com

manpreet
Ms.Bhumika Singh  

Project Scientist

Email Id : bhumikasingh0623@gmail.com

bhumika
Ms. Akshata Hegde  

Doctorate Student

University of Missouri Columbia 

Email Id : akshata.h101@gmail.com

Akshata
Ms. Smriti Pranjal  

PhD. Scholar

University of Kansas

Email Id : pranjalsmriti212@gmail.com

Smriti
Ms. Raushan Anjum  

PhD. Scholar


Email Id : anjum.official2001@gmail.com

Raushan
Ms. Palak Aggarwal  

Project Scientist


Palak
Ms. Akansha Kesharwani  

Project Scientist


Email Id : akankshakesharwani444@gmail.com

Akansha
Ms. Kopal Sharma  

Project Associate


Mr. Devendra Prajapat  

Project Scientist


Email Id : devendrasiyota@gmail.com

Devendra
Dr. Prashant Singh Rana  


Project Scientist

Email Id : psrana@gmail.com

Prashant